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Intestinal Permeability

Hałasa M, Maciejewska D, Baśkiewicz-Hałasa M, Machaliński B, Safranow K, Stachowska E. Oral Supplementation with Bovine Colostrum Decreases Intestinal Permeability and Stool Concentrations of Zonulin in Athletes. Nutrients. 2017 Apr 8;9(4). pii: E370.


• Double-blind placebo-controlled study (n=16) compared 20 days supplementation with either 500 mg of bovine colostrum (BC) or placebo (whey protein) during peak athletic training. 
• Gut permeability status was measured by differential absorption of lactulose and mannitol (L/M urine test) and stool zonulin concentration. 
• BC supplementation decreased and mostly restored to normal the two indicators of intestinal permeability.


CONCLUSION: Bovine colostrum supplementation is safe and effective for decreasing intestinal permeability in athletes who are at increased risk of developing intestinal permeability. BC may have a preventative role in healthy people by restoring gut status following either antibiotic or NSAID use.


Our Mission

Colostrum Therapy is Nature’s first food providing the foundation of our immune system. We offer this place to dialogue with physicians, healthcare professionals and interested individuals dedicated to improving health and reducing our reliance on traditional medical processes that offer little in preventative care. We welcome those who seek the truth, take responsibility for their health and want to improve patient health outcomes without creating side effects. This site is dedicated to Kaye Wyatt 1942-2006 for her dedication to sharing colostrum’s incredible healing story. It is to her we owe a debt of everlasting gratitude.

How to Use Colostrum-LD® (7:33 mins)

Douglas Wyatt, Founder and CEO of Sovereign Laboratories demonstrates how easy it is to make a delicious drink with Colostrum-LD without losing any of the nutritional benefits. For further information, go to


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