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  • Colostrum V6
  • What is Anti Aging with Doug Wyatt
  • Doug Wyatt: The Colostrum Story
  • Leaky Gut: The Source of Chronic Conditions
  • Why Colostrum? Overview
  • Doug Wyatt: How Leaky Gut Syndrome Affects Our Health
  • CBS Report:  Journey to Health

The importance of colostrum for infants who are not breastfed

Maternal milk offers passive protection to a newborn infant against enteric pathogens, primarily via the transfer of immunoglobulins and growth factors from mother to infant. The historical concept of `immune milk’ (the transfer of passive immunity via lacteal antibodies) dates back to the 1950’s. In the 1960’s, the underlying mechanisms of passive immunity were realized when the chemical structure of immunoglobulins was discovered. Later in the 1970’s, the secretory immune system was identified which gave way to the role of secretory antibodies in the

prevention or treatment of enteric infections in mammals.

Since the 1980’s, there has been considerable interest in utilizing antibodies from the milk and colostrum of heterologous species, particularly ruminants. Studies show that bovine antibodies can be effective in the prevention or treatment of human and animal diseases caused by enteropathogenic microbes (bacteria, viruses, protozoans, and fungi). Bovine colostrum is the most prevalent preparation available today, and it passes immunity to all the disease-causing pathogens that the cow has encountered in her lifetime, including the antibodies she received from her mother – a broad spectrum pharmacy. The efficacy of any bovine colostrum supplement is determined by the antimicrobial activity of the specific antibodies and complement factors, which must be preserved during the manufacturing process.

Bovine colostrum influences the immune system in two ways. First, by stimulating it to fight infection and second, to modulate it up or down depending on the most efficacious outcome. The newborn gut is unique in that it has not completed maturation at the time of birth and needs the growth factors and other components of colostrum to complete its development. Immunoglobulins are easily assimilated into the newborn’s body via the GI tract. Colostrum-LD® has been tested for the active antibodies against the following disease-causing microbes:


Bacillus cereus

Streptococcus pyogenes

Streptococcus agalactiae

Streptococcus pneumoniae

Streptococcus mutans

Staphylococcus epidermidis

Staphylococcus aureus

Listeria monocytogenes

Yersinia enterocolitica

Escherichia coli

Escherichia coli O157:H7

Haemophilus influenzae

Campylobacter jejuni

Helicobacter pylori

Salmonella enteritidis

Salmonella typhimurium

Klebsiella pneumoniae

Propionibacterium acnes

Vibrio cholera





Dengue virus


Epstein-Barr virus

Enterovirus 71


Hepatitis C virus

Herpes viruses      


Human Papilloma virus


Japanese encephalithis


Polio virus

Respiratory syncytial virus


St. Louis virus

West Nile virus

Yellow fever virus



Candida albicans



Common Conditions Affecting Infants & Young Children

Diarrheal Disease
Diarrhea is especially lethal to infants and worldwide, it is the second leading cause of death in infants. Antibiotics are ineffective against virus-caused diarrhea, yet Colostrum-LD® has antibodies against many pathogens, including rotavirus which is very common in infants in young children.
Chronic diarrhea caused by opportunistic Cryptosporidia and rotavirus is potentially fatal in children with AIDS because it causes muscle wasting and insufficient nutrient absorption in the gastrointestinal tract. The immunoglobulins in bovine colostrum help fight pathogens and IGF-1 increases muscle mass.


Respiratory Disease

Infants, particularly those born prematurely, are most susceptible to diseases affecting the lungs and respiratory tract because their immune systems are not fully developed. Respiratory Viral Syndrome (RVS) is a common cause of infant mortality in the first two years. With no effective vaccine available, the administration of RVS immune prophylaxis is a viable solution. Research shows that lactoferrin and Proline-Rich Polypeptides (PRPs) in colostrum block entry of the virus into cells, either by blocking cellular receptors, or by direct binding to the virus particles. Seasonal influenza is also a concern for infants and young children, and in the absence of vaccination, bovine colostrum is a viable alternative. Viralox® contains Proline-Rich Polypeptides (PRPs) and lactoferrin. This oral spray is easily administered to infants and young children. Colostrum-LD® can be added to infant formula, milk, applesauce, yogurt for easy ingestion at most ages.


Allergies (including Milk Allergy)
Approximately one out of twenty infants is unable to tolerate the caseins in cow’s milk/colostrum. Thus, cow’s milk should not be introduced into the diet until this allergy is alleviated, so as to avoid any potential adverse reactions. Proline-Rich Polypeptides (PRPs) in colostrum modulate the pro-inflammatory cytokines, which can help improve or eliminate symptomatology of both allergies and autoimmune diseases. Additionally, PRPs inhibit the overproduction of lymphocytes and T-cells and ameliorate the major symptoms observed in allergies and autoimmune disease (pain, swelling and inflammation). Colostrum IC® (oral Immune Concentrate spray) is suited for children under two years of age who have not yet been exposed to either cow’s milk or cow’s colostrum.


Colostrum Supplementation: Literature Summary
Studies with bovine colostrum have demonstrated the antiviral activity against rotavirus, the primary cause of diarrhea in infants and young children (Sarker SA, et al. 1998; Ylitalo S, et al. 1998; Mitra AK, et al. 1995; Davidson G, et al. 1989; Brüssow H, et al. 1987; Yolken RH, et al. 1985).


Bovine colostrum supplementation has also been shown to be a useful method, in addition to known medical and psychological treatments, to increase the weight of children with nonorganic failure to thrive (Panahi Y, et al. 2010).


Oral lactoferrin (a component of colostrum) prophylaxis reduces the incidence of late-onset sepsis in infants weighing less than 3.3 pounds and most effective in infants weighing less than 2.2 pounds (Pammi M, Abrams SA. 2011).


In a case study of a commercial hyperimmune bovine colostrum with potent anticryptosporidial activity, a four year old child with AIDS and severe cryptosporidiosis-associated diarrhea experienced significant clinical improvement in the diarrhea and permanent elimination of the parasite from the gut (Shield J, et al. 1993). In another case study of bovine colostrum, a three year old child with acute cryptosporidia caused diarrhea was treated and recovered within two weeks (Heaton P. 1990).


Lysozyme, which is added to formulas but found in colostrum naturally, is beneficial for the treatment of periodentitis and the prevention of tooth decay. Milk enriched with lysozyme has also been used to feed premature infants suffering from concomitant diseases. (Zimecki M, Artym J. 2005).


Growth Factors in Bovine Colostrum
Growth factors play an important role in maintaining the human body by stimulating cell growth, proliferation, differentiation and migration; responsible for repair of leaky gut epithelia; bone remodelling and maintenance; fracture repair; wound healing; increased collagen production; and growth of blood vessels into damaged areas. There is an increasing use of growth factors for the treatment of hematologic and oncologic diseases and cardiovascular diseases. The most significant growth factors in bovine colostrum for the infant/child’s benefit include: Insulin-like Growth Factor, Epithelial/Epidermal Growth Factor, Transforming Growth Factor, and Vascular Endothelial Growth Factor.


Insulin-like Growth Factor I
(IGF-1) – a protein hormone with a similar structure to insulin and a major growth factor that stimulates cell proliferation in wounds.

Insulin-like Growth Factor II (IGF-2) – a protein hormone with a similar structure to insulin and a major fetal growth factor; promotes growth during gestation.

Epithelial/Epidermal Growth Factor (EGF) – stimulates the proliferation and differentiation of epidermal cells, including the intestinal lining, to maintain gut integrity.

Transforming Growth Factor Beta 1 & 2 (TGF-β1, TGF-β2) – controls cell growth, proliferation, differentiation, and apoptosis; stimulates production of IgA by B lymphocytes; is a vital factor in skeletal growth, bone mass maintenance, and fracture healing.

Vascular Endothelial Growth Factor (VEGF) – creates new blood vessels during embryonic development and new blood vessels after injury.


COLOSTRUM IC® (Immune Concentrate Oral Spray)
A world renown PhD and colostrum specialist recently explained the attenuation of cow’s milk allergy:
Since many infants are unable to tolerate caseins in cow’s milk, Colostrum IC® is recommended for two weeks prior to introducing cow’s milk or cow’s colostrum into the diet, particularly if the child is under two years of age. PRPs and growth factors in bovine colostrum modulate the casein sensitivity and restore homeostasis.




The newborn gut is unique in that it has not completed maturation at the time of birth and needs the growth factors and other components of the mother’s colostrum to complete its development. This incomplete development of the gut is of benefit to the newborn as it allows large proteins, such as immunoglobulins, to easily enter the body. Immunoglobulins in colostrum and mother’s milk bind to disease-causing pathogens on the mucosal surfaces of the GI tract, thereby preventing them from colonizing and causing infection. This modulation by the immune system creates passive immunity for the infant.


Early weaning or exclusive formula use deprives the child of the immunity provided by the mother Immunoglobulins are not present in pasteurized milk or infant formula. Breastfeeding not only helps prevent disease in infants, but research shows that longer breastfeeding is associated with better mental health through childhood and into adolescence.


In modern times, the length of breastfeeding has been determined by social norms, mothers returning to the workplace, and the successful marketing of infant formulas. From 1900 to 1960, negative attitudes caused a significant decline in breastfeeding, however, the trend has been reversing. Experts now recommend that children be breastfed within one hour of birth (for mother’s colostrum), exclusively breastfed for the first six months, and subsequently breastfed until age two complimented with age-appropriate and nutritionally adequate foods.


A note about infant formulas: these are basically “junk food”. Although infant formulas contain protein, fats, carbohydrates, vitamins, and minerals, they contain none of living components present in bovine colostrum and mother’s milk. Formulas simply cannot provide protection against disease-causing pathogens which attack an infant’s immature immune system. If we rob children of these living components, bovine colostrum is the best substitute we presently have.


A note about breast milk sharing: a recent study showed that while good intentioned, 74% of breast milk samples purchased via the internet contained infectious bacteria and 21% contained cytomegalovirus (a herpes-type virus). Mothers can feel safe knowing that bovine colostrum is an alternative way to impart the “life-giving” substances without the potential risks of breast milk sharing.


When mothers discontinue breast feeding before the age of two, bovine colostrum supplementation is strongly recommended for continued support and growth of all body tissue for optimum development and health.


Liposomal Delivery & Standardization


To achieve the gastrointestinal benefits of bovine colostrum, it is crucial that the active components will bypass digestion in the stomach and be bioavailable for uptake and distribution to the body’s cells. Additionally, colostrum must be soluble for free dispersion throughout the GI tract as well as be able to readily disperse in water or formula. Liposomal Delivery enhances the bioavailability, and extensive research shows that such an enhanced delivery method allows ingested bovine colostrum to achieve the intended results. When selecting a bovine colostrum supplement, look for one that is GMP certified, contains a standardized content of active components, is flash pasteurized without loss of effectiveness, and is derived from first-milking pastured cows.


Safety of Bovine Colostrum Supplements


No significant health risks have been reported during or after oral ingestion of immune milk or colostral preparations. Colostrum supplementation is generally regarded as a non-invasive intervention, and therefore, safe. Bovine colostrum is ideal for formula-fed infants or those with limited breast milk feeding (after potential casein allergy is ameliorated). Infants with specific health issues, such as pathogen-induced diarrhea, may have successful resolution without the side effects of pharmaceutical drugs.



This information is copyrighted and may not be reproduced without
express permission from the Center for Nutritional Research.












Colostrum Patient Education Compendium







Your registration gives you access to treatment protocols, clinical studies, success stories, and wholesale pricing on Colostrum-LD®. This is only available to licensed medical providers and INFRA members. Medical licensure or proof of INFRA membership will be verified prior to account approval. 
Patients may purchase Colostrum-LD at our retail site. PRO Colostrum-LD products are exclusively available to patients through licensed medical providers. PRO Colostrum-LD may be purchased through licensed medical providers registered with our direct to patient fulfillment program. Referrals are required for all patient orders at


A minimum order of $200 is required for wholesale pricing. As we transition to PRO Sovereign Laboratories patient fulfillment program, a order minimum of $500 will be required for wholesale pricing effective February 1st, 2019. To learn more about our patient fulfillment program please click here.




December 13-15, 2018
Venetian/Palazzo Resort
Las Vegas, NV
Dr. Marvin Singh, M.D., Gastroenterologist will be immediately available after his talk at our booth to answer your questions on the use of bovine colostrum and gut health on Thursday, Dec. 13th.

February 21-23, 2018
New York Hilton Midtown
New York City, NY
Webinar: "Clinical and Business Applications of Bovine Colostrum"
Wednesday, December 19 at 11 am EST / 8 am PST

May 17-18, 2019
Gaylord Palms Resort
Orlando, FL



For abstracts on these articles, please see Compendium Abstracts in the left column below. 

• Leaky Gut Syndrome: A Modern Epidemic with an Ancient Solution

• Managing Viral Threats with PRPs

• Bovine Colostrum and Athletic Performance

• Anti-Aging Benefits of Bovine Colostrum

• The Importance of Colostrum for Infants Who Are Not Breastfed

• Thriving Baby & Recovering Mother: The Importance of Colostrum

• Colostrum & Pets: An Interview with Steven R. Blake, DVM

• Antibiotic Resistant Superbugs Are Lurking in Our Food Supply

• Colostrum & Allergies: Managing the Immune Response

• The Benefits of HGH Without the Cost or Side Effects

• Blessed Relief from Joint Pain by Boosting Your Immune System

• Answers to Common Questions About Colostrum-LD®

• Colostrum Components Unabridged

• Colostrum Health Benefits

Our Mission

Colostrum Therapy is Nature’s first food providing the foundation of our immune system. We offer this place to dialogue with physicians, healthcare professionals and interested individuals dedicated to improving health and reducing our reliance on traditional medical processes that offer little in preventative care. We welcome those who seek the truth, take responsibility for their health and want to improve patient health outcomes without creating side effects. This site is dedicated to Kaye Wyatt 1942-2006 for her dedication to sharing colostrum’s incredible healing story. It is to her we owe a debt of everlasting gratitude.

Amazon Reviews

"This product has been a miracle for me. Like Doug's wife, I was sick for 6 years and near death. I went to every medical professional possible without obtaining a true diagnosis. After using Colostrum-LD for one month I noticed significant improvement and now several months later and continuing to use the product, I am functioning normally. I tried other colostrum products with no results until a Dr. in Palm Desert, CA recommended this product as the only colostrum that would work. Thank you Sovereign Labs and Doug Wyatt for literally saving my life!" — Jack Faulkner Oregon

Click here to see other reviews

How to Use Colostrum-LD® (7:33 mins)

Douglas Wyatt, Founder and CEO of Sovereign Laboratories demonstrates how easy it is to make a delicious drink with Colostrum-LD without losing any of the nutritional benefits. For further information, go to


Staying Healthy with Peptide Immunotherapy (7:13 mins)

Proline-rich Polypeptides are powerful extracts of immune factors from bovine colostrum that provide immune support. Modulating the immune response of the body helps to quell allergies in an overactive immune system or help boost the immune system when necessary such as in the case of infections. For further information, go to


Vital C-LD: Exceptional Vitamin C Benefits (8:19 mins)

Vitamin C is an essential nutrient but humans don't manufacture vitamin C requiring us to supplement our diets with vitamin C. Vital C-LD with liposomal delivery enables us to absorb 50% of the vitamin C compared to Ester C at 16.5% or ascorbic acid at 8.83%. For more information, go to


GastroDefense G.I. Solutions for Optimum Gut Health (5:21 mins)

Introducing GastroDefense Daily Therapy and GastroDefense Overnight Cleanse are formulated to be companion products to Colostrum-LD®. GastroDefense products help to keep the surface of G.I. tract clear allowing maximum absorption of nutrients. For more information, go to



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